Search on: RHODAMINE 123 
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Descriptor English:   Rhodamine 123 
Descriptor Spanish:   Rodamina 123 
Descriptor Portuguese:   Rodamina 123 
Tree Number:   D03.633.300.953.600.500
Definition English:   A fluorescent probe with low toxicity which is a potent substrate for P-glycoprotein and the bacterial multidrug efflux transporter. It is used to assess mitochondrial bioenergetics in living cells and to measure the efflux activity of P-glycoprotein in both normal and malignant cells. (Leukemia 1997;11(7):1124-30) 
Pharmacological Action:   Fluorescent Dyes
 
See Related English:   P-Glycoprotein
 
History Note English:   99; use RHODAMINE 123 (NM) 1982-98 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   33815 
Unique Identifier:   D020112 

Occurrence in VHL:
 

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